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Top 5 Supplements That Support Wellness on Ozempic

by Support Potens Digital on Oct 03, 2025
Top 5 Supplements That Support Wellness On Ozempic

Ozempic (semaglutide) is getting significant popularity among individuals and has become a well-recognised option for managing type 2 diabetes and supporting weight management.

While it can be highly effective, those on Ozempic always look for additional ways to support their overall wellness, particularly for better digestion, boosting their energy, nutrient absorption, and long-term health.

Here, you must know that there are dietary supplements that can play an essential role in supporting your wellness, provided these supplements are chosen wisely and aligned with your body's changing needs.

You can add the right supplements to your routine to ease common side effects, maintain steady energy, and protect your long-term health while maximising the benefits of Ozempic. Whether it is preventing nutrient gaps or supporting heart and metabolic wellness, supplements can help you feel your best during your Ozempic journey.

Key Takeaways

Which supplements offer the most value with Ozempic? Not everyone requires supplements, but for addressing common gaps and side effects, supplements can be your health game changers.

  • Probiotics ease digestive discomfort.
  • Fibre supports digestion and satiety.
  • Vitamin B12 boosts energy and nerve health.
  • Magnesium promotes balanced metabolism.
  • Omega-3s protect heart and brain health.

Why Complement Ozempic With Supplements?

Consuming supplements can help reduce common side effects, address nutritional gaps, and enhance long-term health outcomes for individuals taking Ozempic.

We all know the primary purpose of Ozempic is to regulate your blood sugar and support weight loss by slowing gastric emptying. However, it can also change your appetite patterns and food intake.

This is why some individuals may consume fewer nutrients than before. Supplements play a supportive role by - 

  • Easing digestive side effects
  • Boosting energy when calorie intake is lower
  • Protecting long-term heart and metabolic health

Note to Remember! Your supplements will not replace Ozempic or diet, but they can enhance overall wellness while the body adjusts.

What Are The Top Supplements People Should Consider While Taking Ozempic?

If you're considering starting the top supplements to take with Ozempic, you don't need to worry! Here are the secret ingredients that can help you stay fit and healthy.

  1. Probiotics for gut health
  2. Fibre supplements for digestion
  3. Vitamin B12 for energy support
  4. Magnesium for metabolic balance
  5. Omega-3 fatty acids for cardiovascular health

Each of these supplements addresses common wellness needs experienced by individuals on Ozempic.

Let’s explore them in detail …

Why Are Probiotics Important For Gut Health While On Ozempic?

Not sure how probiotics can help you? Well, probiotics can help maintain a balanced gut microbiome, which supports digestion and reduces common side effects of Ozempic. This means no more bloating, constipation, and nausea for you.

When starting Ozempic, some individuals report digestive discomfort as their body adjusts to the medication. Probiotics, which are live beneficial bacteria, play a critical role in restoring healthy gut flora.

They can - 

  • Improve nutrient absorption.
  • Reduce gastrointestinal side effects.
  • Strengthen the immune system.

According to a study, probiotics have been shown to influence metabolic health, thereby improving digestion and minimising gastrointestinal side effects. This is especially beneficial for individuals using GLP-1 receptor agonists, such as Ozempic.

Tip to Consider -  Look for multi-strain probiotic formulas containing Lactobacillus and Bifidobacterium, as these are well-researched for digestive health.

How Does Fibre Supplementation Help Improve Digestion On Ozempic?

Are you experiencing constipation after starting Ozempic? We understand your struggles. Fibre supplements can help ease constipation, regulate blood sugar levels, and promote a feeling of satiety. The consumption of fibre supplements will enhance the benefits of Ozempic for weight management.

You may experience digestive sluggishness. Why is that so? Because Ozempic slows gastric emptying. You can add dietary fibre, either through whole foods or supplements, which can help by - 

  • Promoting regular bowel movements
  • Supporting blood sugar control.
  • You will feel full, which means NO unnecessary snacking.

Pro Tip -  The best approach is to start with small doses of fibre supplements. You will soon notice a significant improvement in your health. This will minimise gas or bloating, and always pair them with adequate water.

Why Is Vitamin B12 Supplementation Recommended For Those On Ozempic?

Tired of living with a consistent feeling of being fatigued, and therefore, you feel that you're living a miserable life as you can't achieve much daily?

Taking vitamin B12 regularly can help alleviate this feeling while supporting nerve health. This is highly vital to you, as reduced food intake on Ozempic may limit B12 absorption.

B12 deficiency can lead to tiredness, brain fog, and even long-term neurological issues. Since some individuals on Ozempic naturally eat smaller meals, their intake of B12-rich foods, such as meat, fish, and dairy, may decrease.

Supplementation ensures your body still receives what it needs to - 

  • Produce energy efficiently
  • Support red blood cell formation
  • Maintain healthy nerve function

According to the National Institutes of Health (NIH), nearly 10 to 15% of adults over the age of 60 already experience low B12 levels. This makes supplementation even more critical for those combining Ozempic with a restricted diet.

Not sure which form of vitamin B12 is suitable for you?

Healthcare professionals at iCare Naturals will suggest that Methylcobalamin (a bioactive form of B12) is absorbed more effectively than cyanocobalamin.

How Does Magnesium Contribute To Better Wellness While Taking Ozempic?

Magnesium supports energy metabolism, muscle relaxation, and blood sugar regulation, all of which align with Ozempic's role in improving metabolic health.

Many individuals overlook this extraordinary supplement, which plays a crucial role in over 300 enzymatic reactions in the body. For those on Ozempic, magnesium may help with - 

  • Reducing muscle cramps and restless sleep
  • Supporting stable blood glucose levels
  • Enhancing energy and reducing fatigue

A study published in Diabetology & Metabolic Syndrome shows that magnesium supplementation improves insulin sensitivity, a primary benefit for individuals managing type 2 diabetes.

What to Consider? Magnesium citrate and glycinate are more bioavailable forms of magnesium than magnesium oxide, making them suitable options for supplementation.

Why Are Omega-3 Fatty Acids Valuable For People Taking Ozempic?

Omega-3 fatty acids reduce inflammation, support heart health, and enhance overall metabolic function, complementing the cardiovascular benefits of Ozempic.

Omega-3s, typically derived from fish oil or algae, are well-established for promoting cardiovascular health. Since Ozempic is often prescribed to individuals with diabetes, who face higher risks of heart disease, omega-3s serve as a natural partner supplement.

Benefits include - 

  • Lowering triglycerides
  • Supporting brain function
  • Reducing systemic inflammation

Best Practice -  Aim for 1,000–2,000 mg of combined EPA and DHA daily, unless otherwise directed by a healthcare provider.

Factors To Consider With Ozempic

Always consult your healthcare provider before combining supplements with Ozempic to avoid unnecessary risks.

Are There Any Risks Of Taking Supplements With Ozempic?

Most supplements are safe with Ozempic, but some may interact with medications or cause side effects if taken inappropriately.

Potential risks include - 

  • Digestive discomfort can occur when too many new supplements are introduced at once.
  • Interactions with blood thinners (especially with omega-3 fatty acids).
  • Over-supplementation leading to nutrient imbalances.

Can Supplements Replace Diet And Exercise While On Ozempic?

No. Supplements are supportive, not substitutes. A balanced diet and regular physical activity remain central to long-term wellness.

Are There Risks In Combining Supplements With Ozempic?

Most supplements are safe, but interactions may occur, especially with blood thinners or other prescribed medications. Always consult your healthcare provider first.

Conclusion

Ozempic offers a powerful way to support metabolic health and weight management, but it works best when paired with a holistic approach to wellness. Supplements such as probiotics, fibre, vitamin B12, magnesium, and omega-3 fatty acids can fill nutritional gaps and strengthen overall health.


At iCare Natural, we believe in blending science-backed nutrition with mindful supplementation to support your wellness journey. By choosing carefully, you can ensure that your time on Ozempic is not only effective but also nourishing for your long-term health.

Tags: B12 Supplement, Omega-3, Ozempic, Vitamins B12
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